Mayo Clinic is reshaping the future of healthcare in Arizona. What began as a bold vision in 2018 has grown into one of the most transformative medical expansion projects in the Southwest. The Phoenix/Scottsdale campus, located off Loop 101 and 56th Street, is evolving into a world-class hub that blends patient care, education, research, and innovation.
The Foundation: Arizona. Bold. Forward.
In 2018, Mayo launched its Arizona. Bold. Forward. initiative with a nearly $650–$750 million investment to almost double the Phoenix campus footprint. This phase delivered:
- A 7-story, 583,000-square-foot patient tower
- An expanded emergency department
- 99 new beds (raising the total to 374)
- Five new operating rooms
- New lab and clinical space
This expansion created thousands of new jobs, modernized the patient experience, and set the stage for Mayo’s next phase of growth.
Education & Research: Training the Next Generation
Healthcare innovation doesn’t stop at hospital walls. Mayo has aligned with Arizona State University (ASU) to integrate education and research directly into the campus fabric:
- ASU Health Futures Center (2020): A 150,000-sf, $80 million facility dedicated to nursing, biomedical engineering, and collaborative research.
- Mayo Integrated Education & Research Building (IERB) (2024): A 150,000-sf, $134.6 million center for training medical students and advancing research.
Together, these facilities create a seamless pipeline from education to practice, anchoring Arizona as a national hub for healthcare innovation.
Discovery Oasis: A Biotech Innovation Corridor
In 2021, Mayo purchased 228 acres of adjacent land for its Discovery Oasis vision—a biotechnology corridor designed to attract startups, partners, and biomanufacturing firms. With zoning approved for up to 2.17 million square feet of development, this district is positioned to become a life-sciences powerhouse.
Bold. Forward. Unbound.
The next chapter—Bold. Forward. Unbound.—was announced in 2025 as a $1.9 billion program that will expand clinical space by 60% over the next several years. Plans include:
- 1.2 million square feet of new construction
- 11 additional operating rooms (a 31% increase)
- Two new patient units with 48 more beds
- Imaging upgrades: 62% increase in MRI capacity and 44% increase in CT capacity
- A two-story indoor promenade to connect “care neighborhoods” and improve patient navigation
The project is expected to run through 2031, generating an estimated 3,500 new jobs and cementing Mayo’s role as a global healthcare destination.
Designing for Community & Care
- Site Planning: A structured roadway grid, expanded parking (with EV and bike facilities), and a preserved natural wash corridor will ensure accessibility and sustainability.
- Economic Growth: Thousands of high-skill jobs and biotech partnerships will spark housing demand and development throughout Desert Ridge, North Phoenix, and Scottsdale.
- Patient Experience: Thoughtful design emphasizes intuitive navigation, seamless connections between specialties, and welcoming public spaces.
Why It Matters
Mayo Clinic’s expansion is more than just new buildings—it’s a reimagining of how healthcare, research, and education intersect. Patients will see shorter wait times, more advanced treatments, and an easier journey through the care process. Students and researchers will train alongside world-class physicians. Local communities will benefit from new jobs, new housing demand, and a thriving innovation corridor.
Conclusion
The Phoenix campus expansion is a bold blueprint for the future of healthcare. By doubling down on patient care, education, research, and biotechnology, Mayo Clinic is building not only a hospital, but a healthcare ecosystem—right here in North Phoenix.
